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★★★★★ 4.9 from 135 verified reviews
NEXT-GENERATION PROTECTION

Sunsafe Rx: Natural Anti-Aging Skincare From Within

Topical skincare only treats the surface. Sunsafe Rx supports your skin where it matters most: on the inside. It’s the essential part of your daily skincare routine.

  • Defends your skin and eyes.
  • Health benefits for your whole body
  • Made with Antioxidine®: 15+ powerful antioxidants in one daily capsule
  • Published clinical research behind every ingredient
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Manufactured in the USA FDA-Registered Facility NSF Certified Independently Tested
Clinically-Studied Ingredients

Every ingredient is backed by peer-reviewed research. View studies →

Third-Party Tested

Every batch must pass stringent testing for purity, potency, and heavy metals. Learn more →

★★★★★
“I looked at Sunsafe after my dermatologist recommended it. He said it had superior ingredients. It's priced reasonably, and if it's a better formula like my doctor says then it's a total winner.”
— Kanna S., Verified Customer
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How do I use Sunsafe Rx?

Take 1 capsule per day. Maximum effectiveness is reached after several weeks or longer by taking 1 capsule every day, as your body stores the natural antioxidants over time. For extended time outside, take 1 additional capsule as needed.

What is Antioxidine®?

Antioxidine® is our proprietary complex of the most potent antioxidants selected from across the entire spectrum of antioxidant research. Every ingredient — Polypodium Leucotomos, Green Tea EGCG, Lycopene, Astaxanthin, Lutein, Zeaxanthin, Grape Seed Extract, Omega-3s, Vitamins C & E, Selenium, Zinc, and Beta-Carotene — was individually chosen, at specific concentrations, because the science shows it is among the most effective at protecting your skin from within.

Will this replace my sunscreen?

Sunsafe Rx helps support your skin from the inside. But it is classified as a dietary supplement, not a sunscreen, and is not intended to replace sunscreen lotion, shade, or protective clothing. Think of it as the internal compliment to your skincare routine.

How long until I see results?

The active ingredients accumulate in your system over time. Most customers report noticeable improvements in skin appearance and resilience within 4–8 weeks of daily use. For best results, take consistently every day.

Can I take it with other supplements?

Yes. Sunsafe Rx is formulated from natural plant-based antioxidants and is generally well-tolerated alongside other supplements. If you take prescription medications, consult your healthcare provider before adding any new supplement.

Will it reduce my Vitamin D production?

No. It does not sit on your skin, so it never gets in the way of sunlight making vitamin D.

Is it safe for sensitive skin?

Yes — Sunsafe Rx is taken orally as a capsule, so it has no direct contact with your skin. It contains no synthetic fragrances, parabens, or common topical irritants. It is non-GMO, gluten-free, and manufactured in a cGMP facility.

  • Manufactured in the USA
  • FDA-Registered Facility
  • NSF Certified
  • Third-Party Tested
  • Sold Internationally Since 2010
FEATURED IN

 Sunsafe Rx is a supplement made with ingredients clinically shown to defend your skin and eyes. One capsule per day provides natural, anti‑aging protection and improves the appearance of your skin. 

THE BENEFITS OF SUNSAFE RX

Small Capsule. Outsized Benefits.

It's almost too good to be true. These antioxidants protect your skin. They also decrease the appearance of skin aging, wrinkles, and sun spots.

Additionally, some of them — like lutein and zeaxanthin — protect your eyes. The carotenoids can also reduce blotchiness, even skin tone, smooth pigmentation, and improve the appearance of your skin. And there are other incredible benefits to the vitamins, minerals, polyphenols, carotenes, xanthophylls, and other natural compounds.

It all happens while supporting the health of your whole body.

Defend Against Environmental Stresses

Works systemically to promote your skin's natural cellular defense — from the inside out.

Diminish Skin Aging & Wrinkles

Preserve collagen and elastin, and fight the formation of fine lines, wrinkles, and pigmentation.

Support The Health of Your Eyes

Lutein and zeaxanthin are essential constituents of the retina and help protect your eyes from oxidative stress.

Improve The Appearance of Your Skin

Carotenoids can help reduce blotchiness and even skin tone for a radiant, healthy-looking complexion.

Provide Continuous Full-Body Coverage

Always working. Convenient and easy to use. Isn't messy. Won't rub off, wash away, or expire mid-day.

Maintain The Health of Your Whole Body

Made with antioxidants that fight free radicals generated by both internal and environmental sources.

Allow Your Normal Production of Vitamin D

The ingredients in Sunsafe Rx allow your body to synthesize Vitamin D from sunlight as you normally would — like nature intended.

Support Your Immune System

Antioxidants can naturally bolster your immune system, fighting excessive daily environmental stresses.

WHAT'S INSIDE

Powerful Antioxidants. From Nature.

Sunsafe Rx is made with healthy, natural ingredients from foods and plants and has no added sugar, sodium, yeast, wheat, soy, dairy, gluten, preservatives, artificial colors or flavors. And it's caffeine-free.

Polypodium Leucotomos

A fern extract supporting resilience to environmental exposure.

P. leucotomos has been used in Central America for hundreds of years for its various health benefits, and the leaf extract in Sunsafe Rx has demonstrated unprecedented skin protection.

Green Tea Extract (EGCG)

Rich in EGCG polyphenols that support cells under oxidative stress.

Green tea is loaded with healthy compounds called polyphenols. Sunsafe Rx uses an extract filled with a powerful antioxidant called EGCG that has protective properties in your skin.

Grape Seed Extract

Proanthocyanidins for collagen and environmental defense.

Grape seed extract contains a high concentration of proanthocyanidins: polyphenols with strong antioxidant activity that help maintain connective tissue throughout your body including collagen and elastin, and inhibit DNA damage.

Lycopene

Powerful antioxidant efficient at quenching singlet-oxygen.

A carotene, lycopene is a bright red phytochemical found in many plants, vegetables, and fruits. It is an exceedingly effective antioxidant with many known protective properties.

Lutein

Essential xanthophyll for eye and skin health.

A carotenoid phytochemical xanthophyll, lutein is an antioxidant component of the retina of your eye. Extremely important in eye and skin health, lutein may help protect against age-related degeneration.

Astaxanthin

Powerful xanthophyll from algae with antioxidant defense properties.

Another xanthophyll, astaxanthin is naturally found in algae and some seafood. It is a potent antioxidant that helps protect you from oxidative damage and supports your tissue during exposure to environmental stressors.

Zeaxanthin

Filters high-energy visible light in the eye; supports skin under environmental stress.

Also a naturally-occurring xanthophyll, zeaxanthin is a significant component of the macular area of your eyes and helps defend your skin and eyes in the presence of light.

Omega-3

Essential fatty acids reducing environmental skin stress.

Omega-3 fatty acids include DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). They are most readily available in cold water fish and are required nutrients for human health—including healthy skin.

Carotenes

Alpha and beta carotenes support skin resilience to the elements.

Reddish-orange pigments abundant in some vegetables and fruits, alpha-carotene and beta-carotene can decrease skin sensitivity. These protective antioxidants can also be converted into the active form of Vitamin A (retinal)—crucial to eye function.

Vitamin C

Contributes to normal collagen formation for the normal function of skin.

L-ascorbic acid, also known as Vitamin C, is a vital nutrient in a range of metabolic reactions, including the synthesis of collagen—a major component of the dermal layer of your skin.

Vitamin E

D-alpha-tocopherol for skin vitality.

The Vitamin E in Sunsafe Rx consists of d-alpha-tocopherol—the most active, easily absorbed form. D-alpha-tocopherol is an indispensable lipid and antioxidant that protects your skin from damage.

Zinc

Direct antioxidant activity; contributes to the maintenance of healthy skin.

Zinc is an essential dietary mineral involved in numerous critical functions in your body. In your skin, zinc both provides direct antioxidant protection and is the essential element of the crucial antioxidant enzyme superoxide dismutase.

Selenium

Essential micronutrient supporting immune and cellular defense.

Selenium is an essential dietary micronutrient necessary for normal cellular function. It forms the active center of glutathione peroxidase: an antioxidant enzyme that protects your body—including your skin—from oxidative damage.

Taking a Sunsafe Rx capsule with a glass of water
HOW TO USE

Part Of Your Daily Routine

  • 01

    Take 1 Capsule Per Day

    The antioxidants build up in your skin and body over time for maximal effectiveness.

  • 02

    Heading Outside?

    Take Sunsafe Rx about an hour prior to exposure.

  • 03

    Outside for an Extended Period of Time?

    Take 1 additional capsule as needed.

Sunsafe Rx bottle with capsules on a stone ledge
HOW SUNSAFE RX WORKS

Powerful, Proven Protection

Free radicals created by sunlight, radiation, toxins, pollution -- even your own metabolism -- damage your body. Over time, this damage leads to everything from wrinkles and sun spots to poor vision, decreased energy, and DNA mutations. In effect, you age.

Antioxidants help prevent free-radical damage. But your natural stores are continuously being depleted. And even the most well-intentioned diet doesn’t necessarily provide the proper antioxidants at the most effective concentrations.

Sunsafe Rx is made with specific, powerful antioxidants that defend against the oxidative stress that prematurely ages your skin and damages your eyes. These antioxidants also help prevent free-radical damage throughout your whole body. And they’re continuously working for you. In fact, this isn’t just skincare. It’s the ultimate anti-aging product. It's youthfulness in a capsule.

  • Powerful antioxidants
  • Neutralize free-radicals
  • Healthy for your whole body
A Sunsafe Rx capsule surrounded by its natural antioxidant sources
THE SCIENCE

Sunsafe Rx’s Proprietary Formula

The secret to Sunsafe Rx is Antioxidine®: our proprietary formula made with natural antioxidants proven to protect your skin and eyes and fight the appearance of aging.

But this isn't just any formula. We take precise amounts of the specific ingredients that research shows are the most effective, and cram them all into one capsule.

There's no fluff: just exactly what you need and nothing more. And the effectiveness of these antioxidants is proven by hundreds of clinical trials.

PHYSICIAN'S PICK★★★★★

I recommend Sunsafe Rx to my patients who want comprehensive environmental defense. Napa Valley Bioscience's Antioxidine® formula is unmatched for oral dermal protection.

Dr. ShuklaNewport Beach, CA
CLINICAL DEFENSE

Dermatologists Recommend Sunsafe Rx

Dermatologists recommend Sunsafe Rx because the clinical research shows the ingredients protect your skin and eyes, preserve collagen and elastin, and fight the formation of fine lines, wrinkles, and hyperpigmentation.

  • Supports Skin & Eyes
  • Preserves Collagen & Elastin
  • Fights The Signs of Aging
QUALITY & STANDARDS

Natural. Premium Quality. No BS.

Sunsafe Rx is made with premium natural ingredients. There are NO added preservatives, artificial colors, or flavors.

Each batch is stringently tested and must pass exacting standards for purity, potency, and efficacy. It's screened for heavy metals, contaminants, and other toxins.

It's also sealed in an amber glass bottle — NOT plastic like other inferior products.

And it's manufactured in California in our FDA-registered, NSF-certified facility according to strictly-regulated current GMP standards.

Sunsafe Rx bottle surrounded by the foods and plants its antioxidants come from

Premium Ingredients

Premium natural ingredients sourced from trusted suppliers. No added preservatives, artificial colors, or flavors.

Amber glass supplement jar in golden light

Quality Packaging

Sealed in an amber glass bottle, not plastic like other inferior products.

A gloved hand lifting a capsule from a Sunsafe Rx bottle in the lab

Independent Testing & Approval

Every batch is analyzed by an independent lab for purity and potency, and must pass strict specifications for heavy metals, contaminants, toxins, microbiology, and packaging.

Shipping cartons of Sunsafe Rx bottles beside a clipboard

Certified Facility

Manufactured in California in our FDA-registered, NSF-certified facility according to strictly-regulated current GMP standards.

REAL PEOPLE. REAL RESULTS.

Trusted by Those Who Love Their Skin

★★★★★

Courtney Customer

★★★★★

Gary Customer

★★★★★

Mia Customer

★★★★★

Nickolas Customer

★★★★★

Tiera Customer

VERIFIED REVIEWS

Here's What Customers Are Saying.

4.9
★★★★★
135 verified reviews
VERIFIED BUYERS

Customer Reviews

COMMON QUESTIONS

Frequently Asked Questions

Still have a question? Get in touch

Is Sunsafe Rx a sunscreen?

Sunscreen is defined as a chemical lotion that you put on your skin. Sunsafe Rx is not a sunscreen lotion. It is a nutritional supplement, taken orally, that works from within. It is made with specific antioxidants that have been proven to protect your skin and eyes from free-radical damage, and even decrease skin sensitivities. It should not, however, be considered a sunscreen. Or a magic force field.

How does Sunsafe Rx improve my appearance?

Environmental stresses, including sun exposure, damage the layers of your skin and break down collagen and elastin. Over time, this leads to wrinkles, sun spots, inelasticity, and, consequently, the aging of your skin.

In fact, research shows skin damage from exposure to the elements is the main factor in how young or old you look for your age.

Sunsafe Rx contains ingredients shown to diminish the appearance of skin aging by preserving collagen and elastin and fighting the formation of fine lines, wrinkles, and pigmentation.

By promoting your defenses against the factors that age it, the ingredients in Sunsafe Rx help your skin maintain a more youthful appearance over time.

In addition to promoting skin health, the natural ingredients in Sunsafe Rx have also been shown to enhance the appearance of your skin. These antioxidants help fade signs of skin damage and aging.

Furthermore, the carotenoids in Sunsafe Rx appear to help pigment the depigmented areas of your skin — reducing blotchiness and evening skin tone for a more radiant, healthier-looking complexion.

Why is Sunsafe Rx so healthy?

All of the ingredients in Sunsafe Rx are natural and health-promoting, and the product is free of artificial additives.

The antioxidants in Sunsafe Rx not only protect your skin and eyes, but also confer a wide array of health benefits to your whole body.

Why are the ingredients in Sunsafe Rx so effective?

The secret to Sunsafe Rx is Antioxidine: our proprietary blend of antioxidants and natural food and plant extracts. It takes the ingredients in nature that are most effective and combines them into one product — with the most powerful antioxidants at the right concentrations.

Antioxidine was developed and formulated exclusively by Napa Valley Bioscience for the specific purpose of protecting your skin and eyes while being healthy for your whole body.

There are hundreds of clinical studies and published scientific papers encompassing decades of research that prove the effectiveness of the ingredients contained in the Proprietary Antioxidine Complex in Sunsafe Rx.

You can read some of the research here: Formula Research

Should I still use a topical sunscreen lotion while taking Sunsafe Rx?

The sun can be harmful and ages your skin more than anything else. One of the most important actions you can take to protect your skin and eyes, and look as youthful as possible, is to avoid excessive sun exposure, and always protect yourself while you’re in the sun. This includes covering up and may include a non-toxic sunscreen lotion.

Is Sunsafe Rx FDA approved?

Nutritional supplements (officially called dietary supplements) are regulated by the FDA. All the ingredients in Sunsafe Rx are recognized as safe and approved by the FDA for sale in the United States.

Sunsafe Rx is manufactured in our FDA-registered, NSF certified facility in California according to strictly-regulated Current Good Manufacturing Practices for dietary supplements.

Every Sunsafe Rx ingredient and batch is also stringently tested and must pass exacting standards for quality, potency, and purity.

How Does Sunsafe Rx work?

In your body, free-radicals are continuously generated by both external environmental stresses and by the normal functioning of your metabolism.

Yet free-radicals are often harmful, and there is evidence that free-radicals throughout the body are one of the main contributors to the eventual aging of humans. The better able your body is to prevent the generation of detrimental free-radicals — and neutralize them before they can do extensive harm — the healthier you will be.

Antioxidants help prevent free-radical damage. And Sunsafe Rx contains the natural antioxidants that have been shown, via extensive research, to be the most effective at preventing damage from free-radicals.

Furthermore, these potent nutrients — from a wide array of healthy fruits, vegetables, plants, and animals — are often lacking in the average diet.

Supplementing with Sunsafe Rx contributes to extra antioxidant protection from both external and internal stressors. Not only does Sunsafe Rx support your skin and eyes, it’s also healthy for your whole body.

Who can take Sunsafe Rx?

Sunsafe Rx is formulated for women and men of all skin types and is beneficial to your health year-round. It is made with natural ingredients from foods and plants that can be consumed every day.

How do I use Sunsafe Rx?

Sunsafe Rx is easy to use; just take one capsule per day. If you’re going outside during the day, take it 30-60 minutes prior to exposure. On days with prolonged environmental exposure, take one additional capsule.

For maximum benefit, take Sunsafe Rx daily — even on days you’re not outside — because the natural antioxidants in Sunsafe Rx accumulate in your body (including your skin) over time. Maximum effectiveness is reached after several weeks or more by taking at least one capsule every day.

Use Sunsafe Rx while jogging, biking, golfing, hiking, skiing, surfing, gardening, playing tennis, shopping, driving, and during any other activity outdoors.

Take Sunsafe Rx year-round as a supplement with antioxidant and anti-aging benefits for healthy skin, eyes, and body.

Do I still need my topical routine?

Sunsafe Rx supports your skin and eyes in a different way, where it matters the most — from the inside. It's synergistic and complimentary to your normal skincare routine, so you don't need to change anything.

PREMIUM SKINCARE. FROM WITHIN.

Great Skincare Goes Beyond The Surface.

Discover Sunsafe Rx — a daily antioxidant supplement designed to support skin health from the inside out. And so much more.

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