Frequently Asked Questions

Yes, you will still produce your normal amount of Vitamin D in the sun while using Sunsafe Rx. The antioxidants in Sunsafe Rx have been shown to help fight free-radical damage in skin without affecting the body’s natural production of Vitamin D.

The ingredients in Sunsafe Rx are not only effective but also completely safe. All of the ingredients in Sunsafe Rx are natural, exist in nature, and have been isolated from foods and plants. Moreover, each of these ingredients has been extensively studied, has long-term safety data, and has been consumed for decades without any health or toxicity concerns whatsoever.

Sunsafe Rx does NOT contain any added sugar, sodium, yeast, wheat, soy, dairy, gluten, preservatives, artificial colors, or artificial flavors. Sunsafe Rx is manufactured according to current Good Manufacturing Practices (cGMP), with the highest-quality ingredients available, in a certified manufacturing facility in the United States.

Each of the ingredients in Sunsafe Rx has documented benefits and a proven track record of use. For example, the leaves of Polypodium leucotomos have been used in Central America for hundreds of years as a tea. Known for its health benefits, P. leucotomos leaf extract has been used for protection in Europe for decades. Similarly, green tea has been revered for its medicinal and health-promoting properties for millennia.

All of the other ingredients in Sunsafe Rx and Proprietary Antioxidine Complex, including vitamins, minerals, and antioxidants, are naturally present in a plenitude of common foods and plants known for their nutritional benefits such as tomatoes, guavas, papayas, watermelons, palm fruit, kale, spinach, algae, citrus fruits, eggs, nuts, and/or fish, and many others. Yet it is the isolation and combination of these specific ingredients at precise, complementary concentrations that makes them so effective.

For more information on each of the ingredients in Sunsafe Rx

Nutritional supplements (officially called dietary supplements) are regulated by the FDA. All the ingredients in Sunsafe Rx are recognized as safe and approved by the FDA for sale in the United States. Sunsafe Rx is manufactured in an FDA-registered facility in the USA according to strictly-regulated Current Good Manufacturing Practices for dietary supplements.

Sunsafe Rx is formulated for all skin types. In addition to supporting skin in the presence of environmental stresses across individually unique and diverse skin types, the antioxidants in Sunsafe Rx also provide numerous health benefits for your whole body, and have demonstrated supportive properties for eyes.

The ingredients in Sunsafe Rx help support your skin and eyes but are not intended to prevent you from burning. The longer you stay in the sun the more damage is being sustained by your skin—regardless of whether you burn or not. Sun exposure also ages your skin. It is recommended that everyone avoid excessive sun exposure, and those who are in the sun for a prolonged period of time should use protective clothing, sunglasses, and anon-toxic sunscreen lotion.

A tan is a sign of skin damage; melanocytes produce melanin (the pigment in skin that gives it color) in response to DNA damage. So to prevent or delay tanning means that skin damage has been reduced. The ingredients in Sunsafe Rx have been shown to promote your skin’s defenses against the effects of exposure to the elements, but Sunsafe Rx should not be considered a sunscreen. To prevent sun damage you should avoid sun exposure.

On a different note, some of the carotenoids in Sunsafe Rx have been documented to appear to help pigment areas of skin with depigmentation—reducing blotchiness, evening skin tone, and improving complexion

Sunsafe Rx is formulated for both women and men of all skin types and ages. This product has not yet been tested in children or pregnant or lactating women. Pregnant or lactating women or individuals with special medical needs should consult with their healthcare professional before using any nutritional supplement.

For best results, take one capsule of Sunsafe Rx every day. The natural antioxidants in Sunsafe Rx accumulate in your body over time; maximum effectiveness is reach after several weeks or more by taking one capsule every day—even on days without exposure to the elements. On days with prolonged exposure, take one additional capsule.

Sunsafe Rx is formulated for women and men of all skin types and is beneficial to your health year-round, with or without exposure. It is made with natural ingredients from foods and plants that can be consumed every day

You can use Sunsafe Rx while jogging, biking, golfing, hiking, skiing, surfing, gardening, playing tennis, shopping, driving, and during any other activity outdoors. Use Sunsafe Rx year-round as a supplement with antioxidant benefits for healthy skin, eyes, and body.

Sunsafe Rx is health-promoting and can be taken daily. For more information on how and when to use Sunsafe Rx, click here.

The ingredients in Sunsafe Rx are health-promoting regardless of exposure to the elements. These antioxidants not only support your skin’s natural defenses against exposure, but also help defend against all sources of free-radicals—including environmental stresses and harmful byproducts continuously generated by the body during its normal functioning.

There is evidence that free radicals throughout the body are one of the main contributors to the eventual aging of many living organisms, including humans. The better able the body is to prevent the generation of detrimental free radicals or quench them before they can do extensive harm, the healthier a person will be. The antioxidants in Sunsafe Rx help fight free-radical damage—regardless of how the free radicals were generated.

Sunsafe Rx is formulated with powerful antioxidants that, in addition to supporting the health of your skin and eyes, have been shown to confer numerous health benefits to your whole body.

Sunsafe Rx is made with ingredients that are safe and non-toxic. Under rare circumstances, some people may notice the skin taking on a slightly orange or yellow hue after extended consumption of some of the ingredients in Sunsafe Rx if dramatically exceeding a normal dosage for a prolonged period of time. Please note this is not a toxicity and is not a health concern, but is due to the accumulation of carotenes (for example: lycopene and beta-carotene) in the skin. Called lycopenodermia or carotenodermia, this can occur when people eat large quantities of tomato products or substantial amounts of carrots, for example. While this is, in fact, only beneficial to skin protection, it may be undesirable. If this occurs, simply take a lower dose or stop taking Sunsafe Rx for a few days and the color will disappear on its own. It also means your skin accumulates the ingredients in Sunsafe Rx easier than most people (a good thing!) and you can preferentially benefit from the ingredients in Sunsafe Rx while taking less.

Ultraviolet radiation from the sun is harmful. Care should be taken to protect your skin from sun exposure. Repeated exposure of unprotected skin to ultraviolet radiation may increase your risk of skin aging, skin cancer, and other harmful effects to your skin even if you do not burn. This product is not intended to replace topical sunscreen lotion, and in fact can be used synergistically and safely with a non-toxic topical sunscreen. Of course, you should also use other methods of sun protection (like covering up), and in general avoid excessive sun exposure.

To learn more about the toxicities of many sunscreen lotions and our recommendations on which sunscreen active ingredients to use, click here.

SPF stands for Sun Protection Factor. It is a measure of protection against UVB rays only, and does not quantify whether or not a sunscreen protects you against the deeper penetrating—and possibly more damaging—UVA rays. As governed by the FDA, only topical sunscreen lotions that utilize certain chemicals (many of which may have adverse health implications) can claim an SPF.

Sunsafe Rx works in a different way than chemical sunscreens. The ingredients in Sunsafe Rx promote your skin’s natural defenses against the effects of environmental exposure from within your skin; these specific antioxidants from foods and plants have demonstrated supportive properties. As such, the ability of Sunsafe Rx to support your skin and eyes from environmental stresses cannot be accurately quantified by an SPF value. Sunsafe Rx should not be considered a sunscreen.

It is recommended that everyone avoid excessive sun exposure, and those who are in the sun for a prolonged period of time should use protective clothing, sunglasses, and a non-toxic sunscreen lotion.

Antioxidine is a proprietary formulation of natural antioxidants isolated from foods and plants. In addition to the numerous health benefits conferred by antioxidants to the whole body, these specific antioxidants possess protective benefits, and extensive research confirms that they help defend your skin and eyes against the adverse effects of the environment. Antioxidine was developed and formulated exclusively by Napa Valley Bioscience for the specific purpose of supporting your response to environmental stresses. The result is the revolutionary Sunsafe Rx. The ingredients in Sunsafe Rx, and Antioxidine, also have many other health benefits for your skin, eyes, and body.

Not all nutraceuticals are the same; quality ingredients and manufacturing matter. Sunsafe Rx is a premium product produced using only the highest-quality ingredients available, all sourced from reputable suppliers. All the ingredients exist naturally in foods and plants, and all raw materials are tested prior to manufacturing to ensure purity and effectiveness. Using high-quality ingredients costs more, but when health is concerned we think it is well worth it.

Sunsafe Rx is manufactured according to current Good Manufacturing Practices (cGMP). It is manufactured in a certified, FDA-registered manufacturing facility in the United States (in the state of California), under the highest possible quality standards available. Every finished batch of Sunsafe Rx is also tested to meet exacting standards so you can be assured that exactly what is supposed to be in the product is present—nothing more and nothing less.

The ingredients used to manufacture Sunsafe Rx meet our strict standards and the finished product conforms to established specifications of identity, strength, purity, and composition. Our manufacturing facility is registered and approved to manufacture this product by the State of California Department of Public Health, Food and Drug Branch.

Give it eight weeks, every day. Most people first notice their skin feels calmer after a day outside. The mirror comes later.

Take it all year. Your skin's water bottle is drained by wind, cold, heating and city air too, not just by summer sun. The habit is what keeps the bottle full.

Usually yes. It is made of antioxidants and plant extracts found in food. If you take prescription medicine, check with your doctor.

A fern extract (polypodium leucotomos), green tea, grape seed, lycopene, carotenoids, lutein, zeaxanthin, astaxanthin, vitamins C and E, selenium, zinc and omega-3. The full list with amounts is on the Supplement Facts page.

The ingredients come from foods and plants. There is no added sugar, gluten, soy, dairy, yeast, preservatives, artificial colours or flavours, and no caffeine.

Your skin keeps a bottle of antioxidants to cope with sun, heat, wind and dirty air. Every hour outside takes a sip. Food alone cannot keep the bottle full. Sunsafe Rx fills it every morning.

A helper molecule. Sun and air create wear-and-tear in your skin called free radicals. Antioxidants mop them up. Your skin gets them from food, and uses more when you are outside.

Eating well matters, and it is the base. But an outdoor day drains the bottle faster than a normal diet fills it. Sunsafe Rx adds the 15+ your skin uses most, in the amounts the studies used.

Sunscreen sits on the outside, where you rub it, until it washes off. Sunsafe Rx works from the inside, everywhere your blood goes, all day. One is the umbrella, the other is the water bottle.

Two of the ingredients, lutein and zeaxanthin, are found in the back of the eye. Taking them helps keep the eye's own supply topped up.

Yes, on every ingredient. More than one hundred published studies on people, linked on the Research page. We used the amounts those studies used.

Yes. Outdoor workers, athletes, sailors, golfers, gardeners and runners drain the bottle fastest, so they have the most to refill. Keep your hat and sunscreen too.

It is not made for that and we do not claim it. Its job is to keep your skin's antioxidants topped up. For burning, the answer is sunscreen, shade and time.

It is taken by mouth, so nothing touches your skin. There is no fragrance and nothing to rub on.

Any broad-spectrum sunscreen you will actually use. Many people choose zinc oxide or titanium dioxide. Our sunscreen page covers the pros and cons.

Collagen and elastin are the springs in your skin. Sun, wind and heat wear them down over the years. Antioxidants help your skin cope with that wear, which is what ageing well means.

No product in a capsule does that, and we will not tell you otherwise. It supports the skin you have so it ages well from here.

Carotenoids, the colours in tomatoes and carrots, help skin look even and healthy over time.

Sunscreen, shade, sleep, water and not smoking. Sunsafe Rx is the inside half of that list, not a replacement for the rest.

From $0.91 a day on the 120-capsule bottle, less with a subscription.

You choose how often a bottle arrives. Skip, reschedule, or cancel any time from your account. No calls, no questions.

Sixty days. If it is not for you, return it for a full refund or exchange.

Yes, to most countries. Shipping options show at checkout.

Oral sunscreen is a dietary supplement designed to support the skin’s natural defense against UV-related damage from the inside out. These supplements often contain antioxidants like Polypodium Leucotomos, vitamins, and botanical extracts that help reduce oxidative stress caused by sun exposure. Unlike topical sunscreens, oral sunscreen supplements do not directly block UV rays but may help support overall skin resilience when combined with SPF products.

Oral sunscreen pills may help support the body’s natural antioxidant defenses against UV-induced oxidative stress. Ingredients such as Polypodium Leucotomos are commonly studied for their ability to support skin health during sun exposure. However, dermatologists generally recommend using oral supplements alongside topical sunscreen, protective clothing, and other sun-safe practices for comprehensive protection.

Sunscreen pills are usually considered a complementary option rather than a replacement for traditional sunscreen. While oral sun protection supplements may support skin health and help reduce free radical damage, they typically do not provide the direct SPF barrier offered by topical sunscreens. For best results, many experts recommend combining oral supplements with broad-spectrum sunscreen and sun protection habits.

Many daily sun protection supplements contain antioxidants, carotenoids, vitamins C and E, and botanical extracts such as Polypodium Leucotomos. These ingredients may help support the skin’s response to UV exposure and oxidative stress. The ideal supplement depends on individual skin concerns, lifestyle, and sun exposure levels, so it is important to choose products designed specifically for skin and sun health support.

Natural sun-support supplements often include antioxidants that help neutralize free radicals generated by UV exposure. Common ingredients include Polypodium Leucotomos, astaxanthin, lycopene, beta-carotene, and vitamins C and E. These compounds may help support healthy skin, reduce oxidative stress, and improve overall skin resilience when combined with a complete sun protection routine.

Polypodium Leucotomos is a tropical fern extract commonly used in oral sun protection supplements. Research suggests it may help support the skin’s defense against UV-induced oxidative stress and environmental damage. Many people use it as part of an inside-out skincare routine alongside topical SPF products, especially during extended outdoor exposure.

The best supplement usually depends on ingredient quality, formulation, dosage, and additional antioxidants included in the product. Many users look for supplements that combine Polypodium Leucotomos with vitamins and antioxidants that support skin hydration, collagen health, and defense against environmental stressors. Choosing a reputable brand with transparent labeling is often recommended.

Oral sun protection supplements may help support the skin’s natural resilience to UV exposure, but they should not be viewed as a guaranteed method to prevent sunburn or tanning. These supplements are commonly used to support antioxidant protection and skin recovery. For effective sunburn prevention, experts still recommend broad-spectrum sunscreen, protective clothing, and limiting excessive sun exposure.

People with photosensitive skin sometimes use oral antioxidant supplements to support skin comfort during sun exposure. Ingredients like Polypodium Leucotomos are often discussed in relation to skin sensitivity and UV support. However, individuals with severe photosensitivity or medical skin conditions should consult a healthcare professional for personalized recommendations.

Topical sunscreen creates a protective barrier on the skin’s surface to help block or absorb UV radiation. Oral sunscreen supplements work internally by supporting antioxidant defenses and reducing oxidative stress caused by sunlight. Most experts suggest using both approaches together because oral supplements alone generally do not replace the direct UV-blocking benefits of SPF creams or lotions.

Topical sunscreen remains the primary method recommended for direct UV protection because it provides measurable SPF coverage. Oral sunscreen supplements may help complement this protection by supporting skin health from within. Combining oral antioxidants with a broad-spectrum sunscreen is often considered a more comprehensive strategy than relying on either approach alone.

Sun protection supplements are formulated to support the body’s antioxidant defenses against oxidative stress caused by UV radiation. Ingredients such as carotenoids, vitamins, and Polypodium Leucotomos may help promote healthier skin responses to sun exposure. These supplements are commonly described as “inside-out” skincare support products.

Popular antioxidant supplements for skin support include vitamin C, vitamin E, astaxanthin, lycopene, glutathione, and Polypodium Leucotomos. These ingredients may help reduce oxidative stress associated with environmental factors like sunlight and pollution. Many skin-focused supplements combine several antioxidants for broader support.

Antioxidant supplements may help support healthy skin by reducing free radical damage caused by UV rays, pollution, and daily environmental stress. They are commonly used to support collagen health, skin hydration, and overall skin appearance. Regular antioxidant intake may also help promote a healthier-looking complexion as part of a balanced skincare routine.

Antioxidants help neutralize free radicals that contribute to premature skin aging and environmental skin stress. Many people use antioxidant supplements to support collagen integrity, reduce oxidative damage, and maintain healthier-looking skin over time. While supplements are not a substitute for skincare or sun protection, they may support long-term skin wellness when combined with healthy habits.

The best anti aging supplements for skin protection often contain antioxidants, collagen-supporting nutrients, vitamins, and plant extracts that help reduce oxidative stress caused by UV exposure. Ingredients such as vitamin C, vitamin E, astaxanthin, and Polypodium Leucotomos are commonly included in formulations focused on healthy aging and skin resilience.

Anti-aging supplements that contain antioxidants, collagen-supporting compounds, and skin-nourishing vitamins may help reduce the appearance of wrinkles over time. Ingredients such as hyaluronic acid, vitamin C, astaxanthin, and botanical antioxidants are commonly used to support skin hydration, elasticity, and smoother-looking skin naturally.

Many anti-aging supplements are designed to support skin hydration, collagen production, and antioxidant protection. While results vary between individuals, consistent use alongside healthy skincare habits may help improve overall skin appearance and resilience. These supplements are often used as part of a broader wellness and skincare routine.

Supplements rich in antioxidants, vitamins, minerals, and collagen-supporting nutrients are commonly used to help reduce signs of premature aging. Ingredients such as vitamin C, coenzyme Q10, astaxanthin, and Polypodium Leucotomos may help support healthier skin and reduce oxidative stress caused by environmental exposure.

Natural supplements may help support the skin’s defense against oxidative stress triggered by UV radiation. Ingredients like carotenoids, botanical extracts, and antioxidant vitamins are commonly used to help promote healthier skin responses to sunlight. However, natural supplements should be combined with topical SPF products for comprehensive protection.

There is currently no complete natural replacement for topical sunscreen, but certain supplements and antioxidants may help support the skin’s resilience against UV-related stress. Oral supplements containing Polypodium Leucotomos, carotenoids, and antioxidant-rich ingredients are often used as complementary support alongside sunscreen and protective clothing.

Natural alternatives such as antioxidant supplements, protective clothing, shade, and UV-protective accessories may help support sun safety. However, topical sunscreen remains one of the most effective methods for direct UV protection. Many people combine oral antioxidants with SPF products as part of a complete sun care strategy.

Natural sun protection methods include wearing protective clothing, avoiding peak sunlight hours, staying hydrated, and consuming antioxidant-rich foods and supplements. Ingredients like Polypodium Leucotomos, lycopene, and vitamins C and E may help support the skin’s natural defense system against oxidative stress caused by UV exposure.

Supplements commonly associated with photosensitivity support include antioxidants and botanical extracts that help reduce oxidative stress during sun exposure. Polypodium Leucotomos, vitamin C, vitamin E, and carotenoids are frequently discussed in relation to supporting sun-sensitive skin and improving skin resilience.

People with sun-sensitive skin often look for supplements containing antioxidants and skin-supportive nutrients that may help support the skin’s response to UV exposure. Common ingredients include Polypodium Leucotomos, beta-carotene, astaxanthin, and vitamins C and E. Consulting a healthcare professional is recommended for personalized guidance.